Searchable abstracts of presentations at key conferences in endocrinology

ea0022p742 | Steroid metabolism & action | ECE2010

Tissue expression of the CYP19A1 gene and aromatase protein in male cynomolgus monkeys (Macaca fascicularis)

Pignatti Elisa , Lachhab Asmaa , Casarini Livio , Wistuba Joachim , Schlatt Stefan , Carani Cesare , Simoni Manuela

Objective: Aromatase, the key enzyme involved in estrogen synthesis, is expressed in a variety of cells, including peripheral blood leukocytes (PBLs), and tissues. The systematic study of aromatase expression and activity in different tissues in the human and other primates, however, is difficult and still missing. Although is not really known, aromatase expression in PBLs could be used as parameter of aromatase expression/activity making PBLs a potential alternative for other...